Gas chromatography – Mass spectrometry (GC-MS) profiling reveals newly described bioactive compounds in Citrullus colocynthis (L.) seeds oil extracts

Citrullus colocynthis (L.) (C. colocynthis), commonly known as Handal in Yemen and other Arabic countries, is a plant with wide range of pharmacological properties. These properties are attributed to secondary metabolites, phytochemicals, present the plant. In this study, seed C. were extracted using dichloromethane, resulting oil extract was screened identify active phytoconstituents gas chromatography – Mass spectrometry (GC-MS). The used identification spectrum unknown compounds compared stored National Institute Standards Technology Spectral database (NIST) WILEY library GC-MS. A total fifty five appeared GC-MS chromatogram, twenty-four major bioactive identified study. components found be carotenes, phenols, esters, steroids. From chromatogram dichloromethane seeds extract, some possess actions per information available literature. One component isooctylphthalate (58%), which exhibit strong antimicrobials effect. Therefore, considered natural source isooctylphthalate. results, study first report presence various phytopharmaceutical importance colocynthis.